The concept and the design method of the real-time control under the WinCE operation system is described in this paper by the analysis of the WinCE operation system and its timer. The multimedia timer and the peripheral hardwares are employed in the design. The design and application of the real-time time sequence control in the pressurization and the close-cycle control system of the liquid rocket engine are introduced. The application prospect of the real-time control software design framework based on the multimedia timer is elaborated.